![]() IP alleviates the extreme autonomic reactions after surgery, suggesting that cardiac autonomic regulation is involved in the IP protective mechanism.Whole-body Bio-impedance Technology, utilized in MyNicas, is unique and propriety to Ni Medical. Nonlinear HRV exponent alpha1 is a more sensitive measure to predict the postoperative outcome in CABG patients. The present findings show that cardiac autonomic regulation is impaired after CABG. IP significantly reduced the incidence of postoperative arrhythmias and improved postoperative outcome. No other differences were observed in the changes in linear HRV measures between the groups. The suppressed exponent alpha1 was attenuated in the IP group as compared to controls (P = 0.008). The lower pre- and postoperative exponent alpha1 predict the higher incidence of postoperative AF and worse postoperative outcome. ![]() All time and frequency domain HRV variables as well as nonlinear indexes of HRV, the short-term (4-11 beats) scaling exponent alpha1, were suppressed significantly after surgery in both study groups. Arrhythmias, linear and nonlinear HRV measures were analyzed. Holter data were collected in 86 CABG patients before and after surgery. The IP patients received two periods of 2-min ischemia followed by 3-min reperfusion by aortic cross-clamped. Eighty-six CABG patients were randomized into a control and an IP group. We therefore hypothesis that the protective mechanism of ischemic preconditioning (IP) may involve in cardiac autonomic regulation. Short brief myocardial ischemia has been reported to influence HRV. The clinical relevance of HRV, especially nonlinear HRV in CPB patients has not been well studied. ![]() Heart rate variability (HRV) is the most frequently used noninvasive diagnostic method in the assessment of cardiac autonomic control. ![]()
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